Anti-phospholipid antibody

Autoantibodies directed against phospholipids or phospholipid-binding plasma proteins detected by assays such as lupus anticoagulant and anticardiolipin tests.

Causes

• Antiphospholipid syndrome (hypercoagulable state)

• SLE

• Viral infections: COVID-19, EBV, Hepatitis C, HIV

• Bacterial infections: Lyme disease, treponema

• Medications: Antibiotics, procainamide, quinidine, chlorpromazine, phenytoin