Heart failure

A clinical syndrome caused by structural or functional cardiac abnormality, leading to impaired ventricular filling or ejection, inadequate cardiac output, and elevated intracardiac pressures, typically manifesting with dyspnea, fatigue, and signs of volume overload. Possible causes are coronary artery disease, myocardial infarction, hypertension, cardiomyopathy, heart valve disease, arrhythmia, diabetes, kidney disease, and thyroid problems.