Pancreatic pseudocysts

Encapsulated, non-epithelialized peripancreatic fluid collections containing leaked pancreatic digestive enzymes (especially amylase), with minimal or no necrotic debris, arising as a delayed complication of pancreatic inflammation or injury.

Causes

• Inflammatory causes

  • Acute pancreatitis

  • Chronic pancreatitis

  • Recurrent episodes of pancreatitis

  • Post-necrotizing pancreatitis fluid collections (when necrotic debris has resolved)

• Traumatic causes with or without pancreatic duct disruption

• Iatrogenic causes causing duct leakage

  • Post-endoscopic retrograde cholangiopancreatography (ERCP)

  • Pancreatic surgery

  • Pancreatic biopsy or intervention

• Pancreatic duct obstruction

  • Pancreatic duct strictures

  • Pancreatic duct stones

  • Sphincter of Oddi dysfunction