Anti-cardiolipin antibody

Autoantibody directed against the anionic phospholipid cardiolipin, usually detected by ELISA, classified by isotype (IgG, IgM, IgA) and titer, and associated with:

• Antiphospholipid syndrome

• Thrombosis

• Thrombocytopenia

• Recurrent pregnancy loss

Other causes

• Systemic lupus erythematosus

• Rheumatoid arthritis

• Scleroderma

• Syphilis

• HIV

• Hepatitis B and Hepatitis C

• Malaria

• EBV

• Parasitic diseases

• Drugs: phenytoin, penicillin, procainamide