Bile duct stenosis

Pathologic narrowing of the intrahepatic or extrahepatic bile ducts, most often the common bile duct, resulting in impaired antegrade bile flow and potential upstream biliary dilatation and obstructive cholestasis.

Causes

• Post-surgical complications: Cholecystectomy, liver transplantation

• Inflammation: PSC, pancreatitis, Crohn's disease, diverticulitis, sarcoidosis, choledochulithiasis, cholangitis, HIV-associated cholangiopathy

• Malignancy: Cholangiocarcinoma, pancreatic cancer, gallbladder cancer, liver cancer