Decreased Aldosterone

Below normal level of the hormone aldosteron, leading to impaired renal sodium reabsorption, reduced extracellular volume (hypotension), and a propensity for hyperkalemia, hyponatremia, and normal anion gap metabolic acidosis.

• Upright: 7 - 30 ng/dL (190 - 830 pmol/L)

• Supine: 3 - 16 ng/dL

• 24-Hour Urine: 3 - 25 μg/24 hours

Causes

• Addison's disease (primary adrenal insufficiency)

• Diabetes

• Kidney failure (low renin)

• Medications: ACE inhibitors / ARBs, NSAIDs, Heparin, Diuretics, Calcineurin inhibitors

• Pituitary gland disorders