Elevated VIP

Abnormally increased plasma concentrations of vasoactive intestinal peptide above the upper reference limit (normal range: 0-75 pg/ml or 0-22,2 pmol/l), and may correlate with secretory diarrhea and electrolyte disturbances. It suggests pathological VIP hypersecretion from a neuroendocrine tumor (VIPoma, ganglioneuroma or neuroblastoma).

An increased plasma concentration of vasoactive intestinal peptide (VIP) above the upper reference limit (normal range: ~0-75 pg/mL or ~0-22.2 pmol/L), suggesting pathological VIP hypersecretion, most commonly from a neuroendocrine tumor.

Causes

• Neuroendocrine tumors

  • VIPoma

  • Ganglioneuroma

  • Neuroblastoma