Fat macroglobulinemia

The presence of large fat globules within the circulating blood, typically detected during evaluation for fat embolism syndrome, indicating intravascular fat release and potential microvascular obstruction.

Causes

• Trauma and orthopedic causes

  • Long bone fractures

  • Pelvic fractures

  • Orthopedic surgery

  • Bone marrow transplantation

• Surgical and procedural causes

  • Liposuction

  • Intravenous lipid infusion

• Systemic conditions

  • Corticosteroid therapy

  • Severe acute pancreatitis

  • Sickle cell crisis

  • Severe burns

  • Alcoholic fatty liver disease