Hyperesthesia

Increased sensitivity to sensory stimuli, characterized by pathological augmentation of cutaneous perception and an exaggerated response to normally non-noxious stimuli, commonly associated with neuropathic disorders and altered sensory processing.

Causes

• Peripheral neuropathies

  • Diabetic peripheral neuropathy

  • Alcohol-related neuropathy

  • Vitamin B12 deficiency

• Infectious causes

  • Herpes zoster infection (shingles)

  • Postherpetic neuralgia

• Neurological causes

  • Multiple sclerosis

  • Peripheral nerve injury

  • Central nervous system disorders affecting sensory pathways

• Chronic pain syndromes

  • Complex regional pain syndrome

  • Fibromyalgia

• Medication-related causes

  • Chemotherapy-induced peripheral neuropathy

  • Neurotoxic antibiotics

• Hypothyroidism

• Kidney failure (uremic neuropathy)

• Autoimmune neuropathies

• Entrapment neuropathies