Myocardial hypokinesia

A regional or global reduction in myocardial systolic wall motion due to ischemic, inflammatory, structural, toxic, or electrical abnormalities.

Causes

• Ischemic and vascular causes

  • Myocardial ischemia

  • Myocardial infarction

  • Coronary artery disease

  • Coronary artery spasm

• Inflammatory causes

  • Myocarditis

  • Autoimmune inflammatory myocardial disease

  • Infectious myocardial inflammation

• Cardiomyopathic causes

  • Dilated cardiomyopathy

  • Hypertrophic cardiomyopathy with impaired systolic function

  • Stress-induced cardiomyopathy (Takotsubo syndrome)

• Toxic causes

  • Chemotherapy-related cardiotoxicity

  • Chronic alcohol abuse

  • Cocaine toxicity

• Hypertension

• Valvular heart disease causing ventricular remodeling

• Hypervolemia

• Tachy-brady syndrome

• Infiltrative myocardial diseases:

  • Amyloidosis

  • Sarcoidosis

  • Hemochromatosis

  • Fabry