Sclerotic bone lesion

A focal or diffuse area of increased bone density characterized radiographically by radiodense, hardened, or thickened bone matrix compared with adjacent normal bone.

Causes

• Increased bone formation

  • Enostoses (bone islands)

  • Callus formation during fracture healing

  • Osteomyelitis

  • Osteoid osteoma

• Malignant causes

  • Osteosclerotic metastases

  • Lymphoma

  • Osteosclerotic multiple myeloma

• Metabolic and systemic causes

  • Paget's disease of bone

  • Sickle cell disease

  • Fluorosis

• Other causes

  • Osteopetrosis

  • Chronic osteonecrosis