Uveitis

Inflammation of the uvea, the vascular middle layer of the eye (iris, ciliary body, and choroid), potentially involving adjacent ocular structures and leading to pain, photophobia, decreased visual acuity, and risk of irreversible vision loss. Possible causes are autoimmune diseases (ankylosing spondylitis, sarcoidosis, Crohn's disease, rheumatoid arthritis, lupus, multiple sclerosis), infections (herpes simplex, herpes zoster, syphilis, toxoplasmosis, tuberculosis, Lyme disease), trauma (burns, surgery), and medications (cancer immunotherapy).