Epicanthal folds

Possible causes are normal anatomic variant (especially in infants), specific East Asian ancestries, underdeveloped nasal bridge, and various congenital syndromes (Down syndrome, Fetal alcohol syndrome, Turner syndrome, Noonan syndrome, Blepharophimosis syndrome, Williams syndrome, Zellweger syndrome).

Semilunar vertical folds of skin of the upper eyelid that extend across and partially or completely cover the medial canthus, representing a variation in eyelid anatomy.

Causes

• Physiologic finding in infants

• Genetic: Individuals of East Asian ancestry

• Underdeveloped nasal bridge

• Congenital syndromes

  • Down syndrome

  • Fetal alcohol syndrome

  • Turner syndrome

  • Noonan syndrome

  • Blepharophimosis syndrome

  • Williams syndrome

  • Zellweger syndrome