Increased iodide uptake

An elevated thyroidal accumulation of administered radioactive iodide on uptake testing, reflecting increased iodide trapping and utilization by hyperfunctioning thyroid tissue.

Causes

• Autoimmune causes

  • Graves disease

  • Early Hashimoto's thyroiditis with transient hyperthyroid phase (hashitoxicosis)

• Autonomous thyroid tissue causes

  • Toxic multinodular goiter

  • Toxic nodular goiter

  • Toxic adenoma

• Pituitary-related causes

  • Thyroid-stimulating hormone (TSH)-secreting pituitary adenoma

  • Other rare causes of inappropriate TSH stimulation