Keratic precipitates

Inflammatory cellular deposits, typically composed of macrophages, lymphocytes, and epithelial cells, adherent to the posterior corneal surface (corneal endothelium) due to chronic anterior segment inflammation, particularly anterior uveitis or iridocyclitis.

Causes

• Infectious causes

  • Herpes simplex virus (HSV) anterior uveitis

  • Herpes zoster virus (HZV) ophthalmicus

  • Syphilis

  • Tuberculosis

  • Toxoplasmosis

  • Other bacterial, viral, fungal, or parasitic ocular infections

• Autoimmune and inflammatory causes

  • Anterior uveitis / iridocyclitis

  • Sarcoidosis

  • Fuchs heterochromic iridocyclitis

  • Systemic lupus erythematosus (SLE)

  • Juvenile idiopathic arthritis (JIA)

  • HLA-B27–associated inflammatory disorders

• Traumatic and postoperative causes

• Idiopathic anterior uveitis