Claudication

Painful cramping, fatigue, or discomfort in a lower-extremity muscle group, classically the calves, precipitated by exertion and reproducibly relieved by brief rest, most often due to peripheral arterial insufficiency.

Causes

• Atherosclerosis

• Thrombosis

• Embolus

• Popliteal artery entrapment syndrome

• Cystic adventitial disease

• Fibromuscular dysplasia

• External compression syndromes