Esophageal ulcer

A discrete mucosal break in the esophageal lining extending through the muscularis mucosae, representing an esophageal ulcer.

Causes

• Gastroesophageal reflux disease (GERD)

• NSAIDs retained in the esophagus and dissolving locally

• Infectious causes

  • Candida esophagitis

  • Herpes simplex virus (HSV) infection

  • Cytomegalovirus (CMV) infection

  • Helicobacter pylori infection

• Radiotherapy-induced esophageal injury

• Chemical and mechanical irritation

  • Alcohol consumption

  • Tobacco smoking

  • Corrosive ingestion

  • Recurrent vomiting

  • Traumatic mucosal injury