Inverted T wave

A downward-pointing negative wave on an ECG, reflecting altered ventricular repolarization that may be physiological or associated with ischemia, structural heart disease, or secondary conduction changes. Possible causes are myocardial ischemia/infarction, Wellen's syndrome, ventricular hypertrophy, hypertrophic cardiomyopathy, Takotsubo cardiomyopathy, pulmonary embolism, CNS injury (trauma, stroke, hemorrhage), hypokalemia, digoxin, antidepressants, and sometimes a normal variant in the V1-V3 leads.