Sister Mary Joseph's nodule

A metastatic umbilical or paraumbilical nodule resulting from transcoelomic, lymphatic, or hematogenous spread of advanced intra-abdominal or pelvic malignancy.

Causes

• Gastrointestinal malignancies

  • Gastric cancer

  • Colorectal cancer

  • Pancreatic cancer

• Gynecological malignancies

  • Ovarian cancer

  • Uterine cancer

• Urological malignancies

  • Bladder cancer

  • Prostate cancer

• Other malignancies

  • Lung cancer

  • Breast cancer

  • Lymphoma