Sister Mary Joseph's nodule

A metastatic umbilical or paraumbilical nodule resulting from transcoelomic, lymphatic, or hematogenous spread of advanced intra-abdominal or pelvic malignancy. Possible origins of malignancy are gastrointestinal (stomach, colon, pancreas), gynecologic (ovary, uterine), urologic (bladder, prostate), lung cancer, breast cancer and lymphoma.