Eosinophilia

An abnormal increase in circulating eosinophils (≥500/μL).

Causes

• Allergic and atopic disorders

  • Allergic rhinitis

  • Atopic dermatitis

  • Asthma

  • Food allergy

• Parasitic infections

  • Roundworm infections

  • Tapeworm infections

  • Hookworm infections

  • Other helminthic infections

• Autoimmune and inflammatory disorders

  • Eosinophilic granulomatosis with polyangiitis

  • Inflammatory bowel disease

  • Eosinophilic gastrointestinal disorders

• Drug-related causes

  • Antibiotics

  • Anti-seizure medications

  • NSAIDs

  • Other hypersensitivity drug reactions

• Hematologic and malignant disorders

  • Eosinophilic leukemia

  • Myeloproliferative neoplasms

  • Lymphoma

  • Solid organ malignancies

• Other causes

  • Adrenal insufficiency

  • Autoimmune eosinophilic syndromes

  • Idiopathic hypereosinophilic syndrome