Diagnosis

Liver injury

Traumatic liver injury resulting in subcapsular hematoma or laceration.

Also known as: Liver trauma, Traumatic liver injury

Etiology

Cause [ums]

Pathophysiology [ums]

  1. Blunt injury: Locally fixed under the diaphragm --> susceptible to shear forces from deceleration injuries

  2. Penetrating injury: anterior location and relative large size (gunshot or stab wounds)

  3. Highly vascular parenchyma with thin-walled vessels and high blood flow

American Association for the Surgery of Trauma Liver injury classification:

  1. Grade 1: minor injuries represent 80-90% of all injuries, require observation

    • Hematoma: Subcapsular, non-expanding, <10% of surface area

    • Laceration: Capsular tear, non-bleeding, <1 cm parenchymal depth

  2. Grade 2:

    • Hematoma: Subcapsular, non-expanding, 10-50% of surface area

      or intraparenchymal non-expanding, less than 2 cm in diameter

    • Laceration: Capsular tear, active bleeding, 1-3 cm parenchymal depth, <10cm in length

  3. Grade 3:

    • Hematoma: Subcapsular, >50% of surface area or expanding, ruptured subcapsular hematoma with active bleeding, intraparenchymal hematoma >2 cm

    • Laceration: Capsular tear >3 cm parenchymal depth

  4. Grade 4:

    • Hematoma: Ruptured intraparenchymal hematoma with active bleeding

    • Laceration:  Parenchymal rupture with bleeding involving 25-50% of the lobe

  5. Grade 5:

    • Laceration:  Parenchymal rupture with bleeding involving >50% of the lobe

    • Vascular: Juxtahepatic venous injuries (retrohepatic vena cava/hepatic veins)

  6. Grade 6: Hepatic avulsion

Complications [ums]

Epidemiology

Incidence per 100.000 [ums][8eq][ypa]

Epidemiology chart for Incidence

Symptoms & findings

Symptoms

Hypotension, Tachycardia, Tachypnea

Clinical findings

Hemoperitoneum

Anamneses

Trauma

Localized findings

Pain
Radiates
RUQ (Right Upper Quadrant)
Onset
Acute (minutes)
Pattern
Constant
Quality
CuttingStabbingTearing
Severity
Moderate (4-7)Severe (8-10)
Swelling
Radiates
Abdomen
Onset
Acute (minutes)
Pattern
Constant

Approach

Treatment

Treatment strategy: [8eq][ums]

  1. Nonoperative management: hemodynamic stable, no active bleeding

  2. Therapeutic transcatheter arterial embolism: Grade 1-3 injury and fluid demand <2L/h

  3. Surgery: If hemodynamic unstable patient

    • Perihepatic packing

    • Mesh rapping

    • Resection debridement

    • Anatomical resection

    • Complete vascular isolation with veno-venous bypass and portocaval shunt

    • Liver transplantation

Differential diagnoses

Hypovolemia, Internal hemorrhage, Ruptured ectopic pregnancy, Sepsis, Shock


References

[1] Taghavi S, Askari R. Liver Trauma. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK513236/

[2] Chien LC, Lo SS, Yeh SY. Incidence of liver trauma and relative risk factors for mortality: a population-based study. J Chin Med Assoc. 2013 Oct;76(10):576-82.

[3] Wiik Larsen J, Søreide K, Søreide JA, Tjosevik K, Kvaløy JT, Thorsen K. Epidemiology of abdominal trauma: An age- and sex-adjusted incidence analysis with mortality patterns. Injury. 2022 Oct;53(10):3130-3138.

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