Cushing's triad

The clinical constellation of systolic hypertension with widened pulse pressure, bradycardia, and irregular or shallow respirations, classically reflecting a late brainstem-mediated response to markedly elevated intracranial pressure and impending herniation.

Causes

• Traumatic brain injury

• Intracranial hemorrhage

• Stroke

• Brain tumor

• Central nervous system (CNS) infection

• Hydrocephalus