Fasciculations

Spontaneous, involuntary, localized muscle contractions and relaxations caused by spontaneous discharge of a lower motor neuron or its axon, producing visible or palpable muscle twitching.

Causes

• Physiological triggers

  • Stress

  • Fatigue

  • Sleep deprivation

  • Intense physical exercise

• Electrolyte disturbances

  • Magnesium deficiency

  • Calcium deficiency

  • Potassium deficiency

• Metabolic conditions

  • Kidney disease

  • Hyperthyroidism

• Neurological disorders

  • Benign fasciculation syndrome

  • Amyotrophic lateral sclerosis (ALS)

  • Spinal muscular atrophy

  • Peripheral neuropathy

• Medications and substances

  • Anticholinergic drugs

  • Steroids

  • Diuretics

  • Caffeine

  • Amphetamine

  • Nicotine