Diagnosis
Acoustic neuroma
Benign intracranial, extra-axial tumor that arise from the Schwann cell sheath investing either the vestibular or cochlear nerve.
Also known as: Acoustic neurilemoma, Acoustic neurinoma, Acoustic neurofibroma, Vestibular neuroma, Vestibular Schwannoma
Etiology
Causes
Conductive hearing loss: cerumen, foreign body, neoplasm, swelling/stenosis of the canal, Perforated tympanic membrane, Ossicular discontinuity, Otosclerosis, Fluid, scarring.
Sensorineural hearing loss: Neuronal damage by intense noise, barotrauma, viral infection, ototoxic drugs (aminoglycosides), Presbyacusis, Iatrogenic, Temporal bone fracture, Meningitis, Cochlear otosclerosis, Menieres disease, Acoustic neuroma.
Pathophysiology
Tumor growth occupy the cerebellopontine angle of the internal auditory canal and gradually compresses vestibular fibers on the surface
Complications [4tk]
Injury to the inferior cerebellar arteries
Neurological injury
Brain herniation
Brain hemorrhage
Injury to the cerebellum
Facial paralysis
Hearing loss
Risk factor
Exposure to high-dose ionizing radiation
Associated with neurofibromatosis types I and II
Epidemiology
Incidence per 100.000 [9rn][4tk]
Symptoms & findings
Symptoms
Ataxia, Facial nerve paralysis, Headache, Hearing loss, Tinnitus, Vertigo
Clinical findings
None listed.
Anamneses
None listed.
Localized findings
Approach
Otoscopy
Weber test
Rinne test
Audiogram
CT caput
Biopsy
Treatment
Over a 5-year period, ~50% of tumors grow with a risk of hearing loss
Observation with imaging/audiologic evaluation (elder patients, small/asymptomatic tumors) [5oq][4tk]
Stereotactic radiosurgery
Surgical removal
Differential diagnoses
Arachnoid cyst, Arteriovenous malformation, Cerumen, Cholesteatoma, Cholesterol cyst, Craniopharyngioma, Dermoid Cyst, Ependymoma, Epidermal cyst, Facial neuroma, Foreign body, Glioma, Granuloma, Hamartoma, Hemangioma, Lipoma, Lymphoma, Meniere disease, Meningioma, Meningitis, Otitis media, Otosclerosis, Pituitary adenoma, Presbyacusis
References
[1] Greene J, Al-Dhahir MA. Acoustic Neuroma. [Updated 2023 Aug 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470177/
[2] Reznitsky M et al. Epidemiology Of Vestibular Schwannomas - Prospective 40-Year Data From An Unselected National Cohort. Clin Epidemiol. 2019 Nov 8;11:981-986.
[3] http://emedicine.medscape.com/article/882876 (2014-01-02); [Medscape]