Diagnosis

Pilonidal disease

A cystic inflammatory process at or near the cranial edge of the gluteal cleft.

Also known as: Pilonidal cyst, Pilonidal sinus

Etiology

Cause [7e5]

Pathophysiology

  1. Sex hormones affect the pilosebaceous glands production

  2. Trapped hair follicles --> distension --> folliculitis --> edema --> follicle occlusion

  3. The infected follicle expands and ruptures into the subcutaneous tissue --> pilonidal abscess

Risk factors

Complications [7e5]

Epidemiology

Incidence per 100.000 [vwa][bic]

Epidemiology chart for Incidence

Symptoms & findings

Symptoms

Chills, Dyschezia, Fever, Malaise

Clinical findings

Elevated CRP, Elevated Sedimentation Rate, Leukocytosis

Anamneses

None listed.

Localized findings

Pain
Radiates
AnusRegio glutealis
Onset
Gradual (days)
Pattern
ConstantIncreasing
Severity
Moderate (4-7)Severe (8-10)
Rash
Radiates
AnusRegio glutealis
Distribution
Localized
Lesion type
ErythemaPlaqueAbscess
Color
Red
Associated symptom
BleedingDischargePainSwelling
Palpation
BlanchingFluctantPainWarmth

Approach

Treatment

  1. Prophylaxis: Laser epilation [3nm][7e5]

  2. Nonoperative management: no abscess, only cellulitis

    • Phenol injections

    • Antibiotics

  3. Surgery when abscess: [3nm]

    • Acute abscess: Incision and drainage

    • Definitive treatment: Excision and primary paramedian closure plus antibiotics

    • Recurrent or refractory: Flap-based procedures -> Bascom ‘cleft lift’

Differential diagnoses

Anal fissure, Anorectal abscess, Anorectal fistula, Cellulitis, Crohn disease, Erysipelas, Folliculitis, Furunculosis, Hidradenitis suppurativa, Osteomyelitis, Syphilis, Tuberculosis, Ulcerative colitis


References

[1] Nixon AT, Garza RF. Pilonidal Cyst and Sinus. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557770/

[2] Faurschou IK, Erichsen R, Doll D, Haas S. Time trends in incidence of pilonidal sinus disease from 1996 to 2021: A Danish population-based cohort study. Colorectal Dis. 2024 Nov 3;27(1):e17227.

[3] Doll D, Luedi MM, Wieferich K, Van der Zypen D, Maak M, Glanemann M (2015) Stop insulting the patient: neither incidence nor recurrence in pilonidal sinus disease is linked to personal hygiene. Pilonidal Sinus J 1:11–18

[4] Segre D, Pozzo M, Perinotti R, Roche B; Italian Society of Colorectal Surgery. The treatment of pilonidal disease: guidelines of the Italian Society of Colorectal Surgery (SICCR). Tech Coloproctol. 2015 Oct;19(10):607-13.

[5] http://emedicine.medscape.com/article/192668 (2014-01-02); [Medscape]

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