Diagnostic finding

Cholestasis

A pathophysiologic state characterized by impaired formation, secretion, or flow of bile, leading to intrahepatic or extrahepatic bile retention with consequent accumulation of bile constituents in the liver and systemic circulation.

Causes

  • Gallstones

  • Tumors

  • Pancreatitis

  • Bile duct stricture

  • Viral hepatitis

  • Primary biliary cholangitis

  • Primary sclerosing cholangitis

  • Drugs: Amoxicillin/clavulanate, anabolic steroids, oral contraceptives, alcohol

  • Sepsis

  • Genetic conditions: Progressive Familial Intrahepatic Cholestasis (PFIC)

Also known as: Bile Duct obstruction, Bile stasis, Biliary obstruction

Referencing diagnoses

Note: Lists existing diagnoses in Diagnotize only.