Diagnostic finding

Elevated ALAT

An increase in alanine aminotransferase (ALAT) activity above the upper reference limit (7-45 U/L), indicating hepatocellular injury or necrosis.

Causes

  • Mild elevation (2–3 × upper limit of normal)

    • Vigorous exercise

    • Fatty meal

    • Nonalcoholic fatty liver disease (NAFLD)

    • Medications: Statins, analgesics

  • Moderate elevation (3-10 × upper limit of normal)

    • Viral hepatitis

    • Autoimmune hepatitis

    • Cirrhosis

    • Bile duct obstruction

  • Severe elevation (10-100 × upper limit of normal)

    • Severe acute viral hepatitis

    • Drug-induced liver injury: Paracetamol overdose

Also known as: Elevated alanine aminotransferase, Elevated alanine transaminase, Elevated ALT, High alanine aminotransferase, High alanine transaminase, High ALT, Hypertransaminasemia, Increased alanine aminotransferase, Increased alanine transaminase, Increased ALT, Transaminitis

Referencing diagnoses

Note: Lists existing diagnoses in Diagnotize only.