Diagnosis
Vestibular neuronitis
A benign, self-limited inflammation of the vestibular nerve.
Also known as: Vestibular neuritis
Etiology
Cause [bwu]
Presumed viral infection: the reactivation of latent HSV infection, respiratory viruses (influenza, adenovirus)
Other theories: vascular or immunologic etiology
Pathophysiology [bwu]
Inflammation of the vestibular portion of the 8th cranial nerve
Imbalance of neuronal input between the left and right inner ears --> Nausea, vomiting, and severe spinning vertigo
Complications [bwu]
Benign paroxysmal positional vertigo (BPPV)
Persistent postural-perceptual dizziness (PPPD)
Epidemiology
Incidence per 100.000 [kzm][s3a][rop][mm4][iee][1nd]
Symptoms & findings
Symptoms
Ataxia, Dizziness, Headache, Hearing loss, Nausea, Tinnitus, Vertigo, Vomiting
Clinical findings
None listed.
Anamneses
None listed.
Localized findings
Approach
Clinical diagnosis: [bwu]
Constant symptoms
Worsened with head movement (no triggered)
Symptoms last several days before resolving
Negative HINTs exam (Head Impulse, Nystagmus, and Test of Skew)
Otoscopy
Neurologic exam: Cranial nerve, cerebellum, gait, balance
Examination for nystagmus, electronystagmography, caloric testing
Audiometry
CT caput
MR caput
Treatment
Symptomatic treatment: max 3 days
Antiemetic: promethazine, metoclopramide
Antihistamine: diphenhydramine, meclizine
Benzodiazepines: diazepam, lorazepam
Vestibular rehabilitation
Gaze stability exercises: keeping eyes fixated on a target while moving the head
Habituation: provoke symptoms and then reduce response upon repetition
Functional retraining – including postural control, relaxation, and balance training
Differential diagnoses
Acoustic neuroma, Benign paroxysmal positional vertigo, Cholesteatoma, Labyrinthitis, Lyme disease, Meniere disease, Migraine, Multiple sclerosis, Stroke
References
[1] Smith T, Rider J, Cen S, et al. Vestibular Neuronitis. [Updated 2023 Jul 21]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK549866/
[2] Sekitani T, Imate Y, Noguchi T, Inokuma T. Vestibular neuronitis: epidemiological survey by questionnaire in Japan. Acta Otolaryngol Suppl. 1993;503:9-12.
[3] Adamec I, Krbot Skorić M, Handžić J, Habek M. Incidence, seasonality and comorbidity in vestibular neuritis. Neurol Sci. 2015 Jan;36(1):91-5.
[4] https://emedicine.medscape.com/article/794489
[5] Koo JW, Chang MY, Woo SY, Kim S, Cho YS. Prevalence of vestibular dysfunction and associated factors in South Korea. BMJ Open. 2015 Oct 26;5(10):e008224.
[6] Greco A, Macri GF, Gallo A, Fusconi M, De Virgilio A, Pagliuca G, Marinelli C, de Vincentiis M. Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo? J Immunol Res. 2014;2014:459048.
[7] Jeong J, Nam Y, Oh J, Choi HS. Monthly and seasonal variations in vestibular neuritis. Medicine (Baltimore). 2022 Jul 1;101(26):e29787.