Diagnosis

Chronic sinusitis

An inflammation of the sinus or nasal passages for > 3 months.

Also known as: Chronic rhinosinusitis

Etiology

Cause

Pathophysiology

  1. Inflammation (bacteria, virus, allergy)

  2. Mucosal edema --> mechanical obstruction in the ethmoid, sphenoid, frontal, and/or maxillary sinus cavities

  3. Mucous stagnation inside the sinuses --> rich medium for microbe growth

  4. Unresolved acute sinusitis --> Chronic sinusitis

Classification [azw]

  1. Chronic sinusitis without nasal polyps

  2. Chronic sinusitis with nasal polyps

  3. Allergic fungal rhinosinusitis

Epidemiology

Prevalence per 100.000 [msf][ips]

Epidemiology chart for Prevalence

Incidence per 100.000 [msf][ips]

Epidemiology chart for Incidence

Symptoms & findings

Symptoms

Anosmia, Cough, Epistaxis, Fatigue, Fever, Halitosis, Headache, Malaise, Nasal congestion, Nasal discharge, Post-nasal drip, Pruritus, Rhinorrhea, Sneezing

Clinical findings

None listed.

Anamneses

None listed.

Localized findings

Pain
Radiates
MaxillofacialCavum oris (inside mouth)DentesEars
Onset
Gradual (days)
Pattern
Constant
Severity
Mild (1-3)Moderate (4-7)

Approach

Diagnostic criteria: >12 week with 2 major or 1 major + 2 minor or nasal purulence [msf]

  1. Major factors:

    • Fascial pain/pressure

    • Fascial congestion/fullness

    • Nasal obstruction/blockage

    • Nasal discharge

    • Hyposmia/anosmia

    • Purulence in the nasal cavity

  2. Minor factors:

    • Headach

    • Fever

    • Hallitosis

    • Fatigue

    • Dental pain

    • Cough

    • Ear pain/pressure/fullness

Treatment

  1. Medical treatment --> controlling predisposing factors, treating concomitant infections, reducing edema of sinus tissues, and facilitating the drainage of sinus secretions: [xeu]

    • Steam inhalation

    • Nasal saline irrigation

    • Topical or oral glucocorticoids (if allergy)

    • Antibiotics (if bacteria)

  2. If the above measures fail --> Surgical treatment: re-establish sinus ventilation and to correct anatomical obstruction causing mucosal clearance:

    • Functional Endoscopic Sinus Surgery (FESS)

    • Balloon sinuplasty

    • Caldwell-Luc procedure

    • Inferior antrostomy (naso-antral window)

    • Nasal polyps and fungal sinusitis: surgical removal

  3. Hospital admission:

    • Orbital and intracranial complications

    • Immunosuppressed patients

    • Pediatric patients

Differential diagnoses

Acute invasive fungal sinusitis, Acute laryngitis, Acute sinusitis, Allergic rhinosinusitis, Asthma, Bacterial tonsillitis, Brain abscess, Cancer, Cerebral venous sinus thrombosis, Meningitis, Nasal polyps, Osteomyelitis, Sarcoidosis, Subdural empyema, Wegener's granulomatosis


References

[1] Kwon E, O'Rourke MC. Chronic Sinusitis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441934/

[2] Shashy RG, Moore EJ, Weaver A. Prevalence of the chronic sinusitis diagnosis in Olmsted County, Minnesota. Arch Otolaryngol Head Neck Surg. 2004 Mar;130(3):320-3.

[3] Tan BK, Chandra RK, Pollak J, Kato A, Conley DB, Peters AT, Grammer LC, Avila PC, Kern RC, Stewart WF, Schleimer RP, Schwartz BS. Incidence and associated premorbid diagnoses of patients with chronic rhinosinusitis. J Allergy Clin Immunol. 2013 May;131(5):1350-60.

[4] http://emedicine.medscape.com/article/232791 (2014-01-02); [Medscape]

[5] Toppila-Salmi S, Hällfors J, Aakko J, Mannerström B, Nieminen K, Telg G, Lehtimäki L. The burden of chronic rhinosinusitis with nasal polyps and its relation to asthma in Finland. Clin Transl Allergy. 2022 Oct 9;12(10):e12200.

Scroll to top